Bipolar Research - Bipolar Disorder, Symptoms, Treatment, Depression, Medication

Bipolar Research Today is a free monthly online journal that collates and summarizes the latest research about Bipolar, including details on bipolar disorder, symptoms, treatment, depression, medication.


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Volume 6 (2009), Issue 2 (February)

  1. Ameliorating prefrontal cortical dysfunction in mental illness: inhibition of phosphotidyl inositol-protein kinase C signaling.
    Psychopharmacology (Berl), 202(1): 445-55. [Abstract] [Full-text]
  2. Lithium and cognitive enhancement: leave it or take it?
    Psychopharmacology (Berl), 202(1): 457-76. [Abstract] [Full-text]
  3. Asenapine restores cognitive flexibility in rats with medial prefrontal cortex lesions.
    Psychopharmacology (Berl), 202(1): 295-306. [Abstract] [Full-text]
  4. Neurotoxicity with therapeutic lithium levels: a case report.
    J Psychiatr Pract, 15(1): 60-3. [Abstract] [Full-text]
  5. Psychological processes in bipolar affective disorder: negative cognitive style and reward processing.
    Br J Psychiatry, 194(2): 146-51. [Abstract] [Full-text]
  6. Correlates of treatment-emergent mania associated with antidepressant treatment in bipolar depression.
    Am J Psychiatry, 166(2): 164-72. [Abstract] [Full-text]
  7. The impact of mental illness on cardiac outcomes: a review for the cardiologist.
    Int J Cardiol, 132(1): 30-7. [Abstract] [Full-text]
  8. Manic symptoms during depressive episodes in 1,380 patients with bipolar disorder: findings from the STEP-BD.
    Am J Psychiatry, 166(2): 173-81. [Abstract] [Full-text]
  9. Risks and predictors of readmission for a mental disorder during the postpartum period.
    Arch Gen Psychiatry, 66(2): 189-95. [Abstract] [Full-text]
  10. The intricate link between violence and mental disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions.
    Arch Gen Psychiatry, 66(2): 152-61. [Abstract] [Full-text]
  11. Influence of genes and environment on brain volumes in twin pairs concordant and discordant for bipolar disorder.
    Arch Gen Psychiatry, 66(2): 142-51. [Abstract] [Full-text]
  12. A 51-year-old woman with bipolar disorder who wants to quit smoking.
    JAMA, 301(5): 522-31. [Abstract] [Full-text]
  13. Cost analysis in a Medicaid program for patients with bipolar disorder who initiated atypical antipsychotic monotherapy.
    Curr Med Res Opin, 25(2): 351-61. [Abstract] [Full-text]
  14. Electrophysiological characterization of the effects of asenapine at 5-HT(1A), 5-HT(2A), alpha(2)-adrenergic and D(2) receptors in the rat brain.
    Eur Neuropsychopharmacol, 19(3): 177-87. [Abstract] [Full-text]
  15. Effects of mood stabilizers on brain reward processes in rats: studies using the intracranial self-stimulation paradigm.
    Eur Neuropsychopharmacol, 19(3): 205-14. [Abstract] [Full-text]
  16. Chronic administration of mood stabilizers upregulates BDNF and bcl-2 expression levels in rat frontal cortex.
    Neurochem Res, 34(3): 536-41. [Abstract] [Full-text]
  17. A functional dopamine-beta-hydroxylase gene promoter polymorphism is associated with impulsive personality styles, but not with affective disorders.
    J Neural Transm, 116(2): 121-30. [Abstract] [Full-text]
  18. Neurobiological evidence for thalamic, hippocampal and related glutamatergic abnormalities in bipolar disorder: a review and synthesis.
    Neurosci Biobehav Rev, 33(3): 336-54. [Abstract] [Full-text]
  19. Effects of age, sex, and independent life events on amygdala and nucleus accumbens volumes in child bipolar I disorder.
    Biol Psychiatry, 65(5): 432-7. [Abstract] [Full-text]
  20. An E3 ubiquitin ligase, Really Interesting New Gene (RING) Finger 41, is a candidate gene for anxiety-like behavior and beta-carboline-induced seizures.
    Biol Psychiatry, 65(5): 425-31. [Abstract] [Full-text]
  21. Risk of rehospitalization among bipolar disorder patients who are nonadherent to antipsychotic therapy after hospital discharge.
    Am J Health Syst Pharm, 66(4): 358-65. [Abstract] [Full-text]
  22. Performance of the Mood Disorder Questionnaire (MDQ) according to bipolar subtype and symptom severity.
    Eur Psychiatry. [Abstract] [Full-text]
  23. Nursing children and adolescents with bipolar disorder: assessment, diagnosis, treatment, and management.
    J Child Adolesc Psychiatr Nurs, 22(1): 33-9. [Abstract] [Full-text]
  24. Effects of the brain-derived neurotrophic growth factor val66met variation on hippocampus morphology in bipolar disorder.
    Neuropsychopharmacology, 34(4): 944-51. [Abstract] [Full-text]
  25. Genetics of bipolar disorder: successful start to a long journey.
    Trends Genet, 25(2): 99-105. [Abstract] [Full-text]
  26. Pathophysiology of depression: role of sleep and the melatonergic system.
    Psychiatry Res, 165(3): 201-14. [Abstract] [Full-text]
  27. Family-based association study of the BDNF, COMT and serotonin transporter genes and DSM-IV bipolar-I disorder in children.
    BMC Psychiatry, 9: 2. [Abstract] [Full-text]
  28. Antidepressant-associated mania: soon after switch from fluoxetine to mirtazapine in an elderly woman with mixed depressive features.
    J Psychopharmacol, 23(2): 220-2. [Abstract] [Full-text]
  29. Genomic landscape of a three-generation pedigree segregating affective disorder.
    PLoS ONE, 4(2): e4474. [Abstract] [Full-text]
  30. The association between self-reported anxiety symptoms and suicidality.
    J Nerv Ment Dis, 197(2): 92-7. [Abstract] [Full-text]
  31. The risk for cancer among patients with schizoaffective disorders.
    J Affect Disord, 114(1): 316-20. [Abstract] [Full-text]
  32. Social anxiety symptoms across diagnoses among outpatients attending a tertiary care mood and anxiety disorders service.
    J Affect Disord, 114(1): 305-9. [Abstract] [Full-text]
  33. Psychosocial functioning among bipolar youth.
    J Affect Disord, 114(1): 174-83. [Abstract] [Full-text]
  34. The functional impact of subsyndromal depressive symptoms in bipolar disorder: data from STEP-BD.
    J Affect Disord, 114(1): 58-67. [Abstract] [Full-text]
  35. Sleep functioning in relation to mood, function, and quality of life at entry to the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).
    J Affect Disord, 114(1): 41-9. [Abstract] [Full-text]
  36. Screening for bipolar disorder in a Spanish sample of outpatients with current major depressive episode.
    J Affect Disord, 114(1): 299-304. [Abstract] [Full-text]
  37. Interpersonal functioning in adolescent offspring of parents with bipolar disorder.
    J Affect Disord, 114(1): 122-30. [Abstract] [Full-text]
  38. Temporal lobe volume in bipolar disorder: relationship with diagnosis and antipsychotic medication use.
    J Affect Disord, 114(1): 50-7. [Abstract] [Full-text]
  39. Identifying hypomanic features in major depressive disorder using the hypomania checklist (HCL-32).
    J Affect Disord, 114(1): 68-73. [Abstract] [Full-text]
  40. Early intervention in bipolar disorders: clinical, biochemical and neuroimaging imperatives.
    J Affect Disord, 114(1): 1-13. [Abstract] [Full-text]
  41. Chronic stress and stressful life events in the offspring of parents with bipolar disorder.
    J Affect Disord, 114(1): 74-84. [Abstract] [Full-text]
  42. Corticolimbic metabolic dysregulation in euthymic older adults with bipolar disorder.
    J Psychiatr Res, 43(5): 497-502. [Abstract] [Full-text]
  43. Risk factors associated with lifetime suicide attempts in bipolar I patients: findings from a French National Cohort.
    Compr Psychiatry, 50(2): 115-20. [Abstract] [Full-text]
  44. Predictors of nonadherence among individuals with bipolar disorder receiving treatment in a community mental health clinic.
    Compr Psychiatry, 50(2): 100-7. [Abstract] [Full-text]
  45. Effects of neuronal Kv7 potassium channel activators on hyperactivity in a rodent model of mania.
    Behav Brain Res, 198(2): 481-5. [Abstract] [Full-text]
  46. Association of MDR1 C3435T polymorphism with bipolar disorder in patients treated with valproic acid.
    Mol Biol Rep, 36(3): 495-9. [Abstract] [Full-text]
  47. Stimulation by lithium of the interaction between the transcription factor CREB and its co-activator TORC.
    Biosci Rep, 29(2): 77-87. [Abstract] [Full-text]
  48. Premenstrual mood symptoms: study of familiality and personality correlates in mood disorder pedigrees.
    Arch Womens Ment Health, 12(1): 27-34. [Abstract] [Full-text]
  49. Contrast sensitivity in Parkinson's disease patients with subthalamic nucleus deep brain stimulation.
    Mov Disord. [Abstract] [Full-text]
  50. The generalized anxiety spectrum: prevalence, onset, course and outcome.
    Eur Arch Psychiatry Clin Neurosci, 259(1): 37-45. [Abstract] [Full-text]
  51. Does psychomotor agitation in major depressive episodes indicate bipolarity? Evidence from the Zurich Study.
    Eur Arch Psychiatry Clin Neurosci, 259(1): 55-63. [Abstract] [Full-text]
  52. Lamotrigine-associated rash: to rechallenge or not to rechallenge?
    Int J Neuropsychopharmacol, 12(2): 257-65. [Abstract] [Full-text]
  53. Association of X-box binding protein 1 ( XBP1) genotype with morning cortisol and 1-year clinical course after a major depressive episode.
    Int J Neuropsychopharmacol, 12(2): 281-3. [Abstract] [Full-text]
  54. Survey of Schizophrenia and Bipolar Disorder Candidate Genes using Chromatin Immunoprecipitation and Tiled Microarrays (ChIP-chip).
    J Neurogenet. [Abstract] [Full-text]
  55. Differential deficit in executive control in euthymic bipolar disorder.
    J Abnorm Psychol, 118(1): 146-60. [Abstract] [Full-text]
  56. Enhanced relapse prevention for bipolar disorder: a qualitative investigation of value perceived for service users and care coordinators.
    Implement Sci, 4: 4. [Abstract] [Full-text]
  57. Maintenance treatment of adolescent bipolar disorder: open study of the effectiveness and tolerability of quetiapine.
    BMC Psychiatry, 9: 4. [Abstract] [Full-text]
  58. Family-based association of FKBP5 in bipolar disorder.
    Mol Psychiatry, 14(3): 261-8. [Abstract] [Full-text]
  59. Metabonomic analysis identifies molecular changes associated with the pathophysiology and drug treatment of bipolar disorder.
    Mol Psychiatry, 14(3): 269-79. [Abstract] [Full-text]
  60. Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk.
    Mol Psychiatry, 14(3): 252-60. [Abstract] [Full-text]
  61. Pharmacokinetic profiles of extended release quetiapine fumarate compared with quetiapine immediate release.
    Prog Neuropsychopharmacol Biol Psychiatry, 33(2): 199-204. [Abstract] [Full-text]
  62. Brain glucose metabolism difference between bipolar and unipolar mood disorders in depressed and euthymic states.
    Prog Neuropsychopharmacol Biol Psychiatry, 33(2): 243-50. [Abstract] [Full-text]
  63. Expression of neuronal calcium sensor-1 (NCS-1) is decreased in leukocytes of schizophrenia and bipolar disorder patients.
    Prog Neuropsychopharmacol Biol Psychiatry, 33(2): 229-34. [Abstract] [Full-text]
  64. The leukocytes expressing DARPP-32 are reduced in patients with schizophrenia and bipolar disorder.
    Prog Neuropsychopharmacol Biol Psychiatry, 33(2): 214-9. [Abstract] [Full-text]
  65. Dose trends for second-generation antipsychotic treatment of schizophrenia and bipolar disorder.
    Schizophr Res, 108(1): 238-44. [Abstract] [Full-text]
  66. A prediction rule for diagnosing hypomania.
    Prog Neuropsychopharmacol Biol Psychiatry, 33(2): 317-22. [Abstract] [Full-text]
  67. Expression of mitochondrial complex I subunit gene NDUFV2 in the lymphoblastoid cells derived from patients with bipolar disorder and schizophrenia.
    Neurosci Res, 63(3): 199-204. [Abstract] [Full-text]
  68. Premedication with dexmedetomidine and midazolam attenuates agitation after electroconvulsive therapy.
    J Anesth, 23(1): 6-10. [Abstract] [Full-text]
  69. Long-term safety of divalproex sodium extended-release in children and adolescents with bipolar I disorder.
    J Child Adolesc Psychopharmacol, 19(1): 83-9. [Abstract] [Full-text]
  70. Effectiveness of lamotrigine in maintaining symptom control in pediatric bipolar disorder.
    J Child Adolesc Psychopharmacol, 19(1): 75-82. [Abstract] [Full-text]
  71. Effect of divalproex on brain morphometry, chemistry, and function in youth at high-risk for bipolar disorder: a pilot study.
    J Child Adolesc Psychopharmacol, 19(1): 51-9. [Abstract] [Full-text]
  72. Subcortical differences among youths with attention-deficit/hyperactivity disorder compared to those with bipolar disorder with and without attention-deficit/hyperactivity disorder.
    J Child Adolesc Psychopharmacol, 19(1): 31-9. [Abstract] [Full-text]
  73. The Child Behavior Checklist (CBCL) and the CBCL-bipolar phenotype are not useful in diagnosing pediatric bipolar disorder.
    J Child Adolesc Psychopharmacol, 19(1): 23-30. [Abstract] [Full-text]
  74. Assessment of personality dimensions in children and adolescents with bipolar disorder using the Junior Temperament and Character Inventory.
    J Child Adolesc Psychopharmacol, 19(1): 13-21. [Abstract] [Full-text]
  75. AACAP 2006 Research Forum--Advancing research in early-onset bipolar disorder: barriers and suggestions.
    J Child Adolesc Psychopharmacol, 19(1): 3-12. [Abstract] [Full-text]
  76. An update on the treatment of bipolar depression.
    Expert Opin Pharmacother, 10(2): 161-72. [Abstract] [Full-text]
  77. Expression of RGS4 splice variants in dorsolateral prefrontal cortex of schizophrenic and bipolar disorder patients.
    Biol Psychiatry, 65(6): 541-5. [Abstract] [Full-text]
  78. Elevated cerebrospinal fluid lactate concentrations in patients with bipolar disorder and schizophrenia: implications for the mitochondrial dysfunction hypothesis.
    Biol Psychiatry, 65(6): 489-94. [Abstract] [Full-text]
  79. A non-randomized study to investigate the effects of the atypical antipsychotic aripiprazole on the steady-state pharmacokinetics of lamotrigine in patients with bipolar I disorder.
    Hum Psychopharmacol, 24(2): 145-52. [Abstract] [Full-text]
  80. A systematic review of the evidence of the burden of bipolar disorder in Europe.
    Clin Pract Epidemol Ment Health, 5: 3. [Abstract] [Full-text]
  81. Diminished central nervous 5-HT neurotransmission and mood self-ratings in children and adolescents with ADHD: no clear effect of rapid tryptophan depletion.
    Hum Psychopharmacol, 24(2): 87-94. [Abstract] [Full-text]
  82. Bipolar disorder in the Bulgarian Gypsies: genetic heterogeneity in a young founder population.
    Am J Med Genet B Neuropsychiatr Genet, 150(2): 191-201. [Abstract] [Full-text]
  83. Mitochondrial DNA haplogroup analysis in patients with bipolar disorder.
    Am J Med Genet B Neuropsychiatr Genet, 150(2): 243-7. [Abstract] [Full-text]
  84. Association between depression and the Gln460Arg polymorphism of P2RX7 gene: a dimensional approach.
    Am J Med Genet B Neuropsychiatr Genet, 150(2): 295-9. [Abstract] [Full-text]
  85. Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identification of candidate genes, pathways and mechanisms.
    Am J Med Genet B Neuropsychiatr Genet, 150(2): 155-81. [Abstract] [Full-text]
  86. Convergent genome wide association results for bipolar disorder and substance dependence.
    Am J Med Genet B Neuropsychiatr Genet, 150(2): 182-90. [Abstract] [Full-text]
  87. Psychiatrists' caseload volume, length of stay and mental healthcare readmission rates: a three-year population-based study.
    Psychiatry Res, 166(1): 15-23. [Abstract] [Full-text]
  88. The burden of mental comorbidity in multiple sclerosis: frequent, underdiagnosed, and undertreated.
    Mult Scler, 15(3): 385-92. [Abstract] [Full-text]
  89. An fMRI study of the neural correlates of incidental versus directed emotion processing in pediatric bipolar disorder.
    J Am Acad Child Adolesc Psychiatry, 48(3): 308-19. [Abstract] [Full-text]
  90. Neurocognitive function in pediatric bipolar disorder: 3-year follow-up shows cognitive development lagging behind healthy youths.
    J Am Acad Child Adolesc Psychiatry, 48(3): 299-307. [Abstract] [Full-text]
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Bipolar Research Today Archive:

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Volume 6 (2009)
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Volume 7 (2010)
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Volume 9 (2012)
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Volume 10 (2013)
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Bipolar Books

Understanding the Mind of Your Bipolar Child: The Complete Guide to the Development, Treatment, and Parenting of Children with Bipolar Disorder

Understanding the Mind of Your Bipolar Child: The Complete Guide to the Development, Treatment, and Parenting of Children with Bipolar Disorder