Bipolar Research - Bipolar Disorder, Symptoms, Treatment, Depression, Medication

Bipolar Research Today is a free monthly online journal that collates and summarizes the latest research about Bipolar, including details on bipolar disorder, symptoms, treatment, depression, medication.


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Volume 6 (2009), Issue 5 (May)

  1. A prospective study of the impact of comorbid medical disease on bipolar disorder outcomes.
    J Affect Disord, 115(3): 355-9. [Abstract] [Full-text]
  2. Cardiovascular risk in patients with bipolar disorder.
    J Affect Disord, 115(3): 302-8. [Abstract] [Full-text]
  3. Is the polarity of relapse/recurrence in bipolar-I disorder patients related to serum lithium levels? Results from an empirical study.
    J Affect Disord, 115(3): 466-70. [Abstract] [Full-text]
  4. The relationship of bulimia and anorexia nervosa with bipolar disorder and its temperamental foundations.
    J Affect Disord, 115(3): 309-14. [Abstract] [Full-text]
  5. Self-medication of mood disorders with alcohol and drugs in the National Epidemiologic Survey on Alcohol and Related Conditions.
    J Affect Disord, 115(3): 367-75. [Abstract] [Full-text]
  6. Medication treatment perceptions, concerns and expectations among depressed individuals with Type I Bipolar Disorder.
    J Affect Disord, 115(3): 360-6. [Abstract] [Full-text]
  7. Randomized, placebo-controlled trial of risperidone for acute treatment of bipolar anxiety.
    J Affect Disord, 115(3): 376-85. [Abstract] [Full-text]
  8. A review of the natural course of bipolar disorders (manic-depressive psychosis) in the pre-drug era Review of studies prior to 1950.
    J Affect Disord, 115(3): 293-301. [Abstract] [Full-text]
  9. Opposite effects of high and low frequency rTMS on mood in depressed patients: relationship to baseline cerebral activity on PET.
    J Affect Disord, 115(3): 386-94. [Abstract] [Full-text]
  10. The mood stabiliser lithium suppresses PIP3 signalling in Dictyostelium and human cells.
    Dis Model Mech, 2(5): 306-12. [Abstract] [Full-text]
  11. Reverse translational strategies for developing animal models of bipolar disorder.
    Dis Model Mech, 2(5): 238-45. [Abstract] [Full-text]
  12. Anterior cingulate cortex abnormalities associated with a first psychotic episode in bipolar disorder.
    Br J Psychiatry, 194(5): 426-33. [Abstract] [Full-text]
  13. Neural mechanisms of a genome-wide supported psychosis variant.
    Science, 324(5927): 605. [Abstract] [Full-text]
  14. Increased oxidative stress in submitochondrial particles into the brain of rats submitted to the chronic mild stress paradigm.
    J Psychiatr Res, 43(9): 864-9. [Abstract] [Full-text]
  15. Functional properties of missense variants of human tryptophan hydroxylase 2.
    Hum Mutat, 30(5): 787-94. [Abstract] [Full-text]
  16. Dorsolateral and dorsomedial prefrontal gray matter density changes associated with bipolar depression.
    Psychiatry Res, 172(3): 200-4. [Abstract] [Full-text]
  17. Genomewide association studies: history, rationale, and prospects for psychiatric disorders.
    Am J Psychiatry, 166(5): 540-56. [Abstract] [Full-text]
  18. Diminished P50, N100 and P200 auditory sensory gating in bipolar I disorder.
    Psychiatry Res, 167(3): 191-201. [Abstract] [Full-text]
  19. Increased choline-containing compounds in the orbitofrontal cortex and hippocampus in euthymic patients with bipolar disorder: a proton magnetic resonance spectroscopy study.
    Psychiatry Res, 172(3): 205-9. [Abstract] [Full-text]
  20. Training staff in enhanced relapse prevention for bipolar disorder: rates of uptake and measures of skill and confidence.
    Psychiatr Serv, 60(5): 702-6. [Abstract] [Full-text]
  21. How reviews covered the unfolding scientific story of gabapentin for bipolar disorder.
    Gen Hosp Psychiatry, 31(3): 279-87. [Abstract] [Full-text]
  22. Altered histamine H3 receptor radioligand binding in post-mortem brain samples from subjects with psychiatric diseases.
    Br J Pharmacol, 157(1): 118-29. [Abstract] [Full-text]
  23. Premorbid personality factors in schizophrenia and bipolar disorder: results from a large cohort study of male conscripts.
    J Abnorm Psychol, 118(2): 418-23. [Abstract] [Full-text]
  24. Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.
    Proc Natl Acad Sci U S A, 106(18): 7501-6. [Abstract] [Full-text]
  25. A review of valproate in psychiatric practice.
    Expert Opin Drug Metab Toxicol, 5(5): 539-51. [Abstract] [Full-text]
  26. No differential effect of age on brain matter volume and cognition in bipolar patients and healthy individuals.
    Bipolar Disord, 11(3): 316-22. [Abstract] [Full-text]
  27. Do positive emotions predict symptomatic change in bipolar disorder?
    Bipolar Disord, 11(3): 330-6. [Abstract] [Full-text]
  28. Selective deficits in semantic verbal fluency in patients with a first affective episode with psychotic symptoms and a positive history of mania.
    Bipolar Disord, 11(3): 323-9. [Abstract] [Full-text]
  29. Clinical characteristics of unipolar disorder and bipolar disorder according to the lifetime presence of recurrent panic attacks.
    Bipolar Disord, 11(3): 307-15. [Abstract] [Full-text]
  30. Examination of concordance between maternal and youth reports in the diagnosis of pediatric bipolar disorder.
    Bipolar Disord, 11(3): 298-306. [Abstract] [Full-text]
  31. Differential item functioning of DSM-IV depressive symptoms in individuals with a history of mania versus those without: an item response theory analysis.
    Bipolar Disord, 11(3): 289-97. [Abstract] [Full-text]
  32. Increased trait-like impulsivity and course of illness in bipolar disorder.
    Bipolar Disord, 11(3): 280-8. [Abstract] [Full-text]
  33. No altered dorsal anterior cingulate activation in bipolar II disorder patients during a Go/No-go task: an fMRI study.
    Bipolar Disord, 11(3): 270-9. [Abstract] [Full-text]
  34. Valproate activates the Notch3/c-FLIP signaling cascade: a strategy to attenuate white matter hyperintensities in bipolar disorder in late life?
    Bipolar Disord, 11(3): 256-69. [Abstract] [Full-text]
  35. Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2009.
    Bipolar Disord, 11(3): 225-55. [Abstract] [Full-text]
  36. Observational study designs for bipolar disorder - what can they tell us about treatment in acute mania?
    Prog Neuropsychopharmacol Biol Psychiatry, 33(4): 715-21. [Abstract] [Full-text]
  37. Use of antipsychotics in the treatment of major depressive disorder in the U.S. Department of veterans affairs.
    J Clin Psychiatry. [Abstract] [Full-text]
  38. The safety, acceptability, and effectiveness of acupuncture as an adjunctive treatment for acute symptoms in bipolar disorder.
    J Clin Psychiatry. [Abstract] [Full-text]
  39. Chronic psychotropic drug treatment causes differential expression of Reelin signaling system in frontal cortex of rats.
    Schizophr Res, 111(1): 138-52. [Abstract] [Full-text]
  40. Characterization of affective domains within the nonaffective psychotic disorders.
    Schizophr Res, 111(1): 61-9. [Abstract] [Full-text]
  41. The serotonin transporter gene and disease modification in psychosis: evidence for systematic differences in allelic directionality at the 5-HTTLPR locus.
    Schizophr Res, 111(1): 103-8. [Abstract] [Full-text]
  42. Tako-tsubo cardiomyopathy following electroconvulsive therapy.
    J Cardiovasc Med (Hagerstown), 10(4): 333-5. [Abstract] [Full-text]
  43. Aberrant amino acid transport in fibroblasts from patients with bipolar disorder.
    Neurosci Lett, 457(1): 49-52. [Abstract] [Full-text]
  44. Mood stabilizing drugs lamotrigine and olanzapine increase expression and activity of glutathione s-transferase in primary cultured rat cerebral cortical cells.
    Neurosci Lett, 455(1): 70-3. [Abstract] [Full-text]
  45. Serum brain-derived neurotrophic factor (BDNF) is not associated with response to electroconvulsive therapy (ECT): a pilot study in drug resistant depressed patients.
    Neurosci Lett, 453(3): 195-8. [Abstract] [Full-text]
  46. Bipolar and major depressive disorder: neuroimaging the developmental-degenerative divide.
    Neurosci Biobehav Rev, 33(5): 699-771. [Abstract] [Full-text]
  47. Regional brain gray matter abnormalities in patients with bipolar II disorder: a comparison study with bipolar I patients and healthy controls.
    Neurosci Lett, 456(1): 44-8. [Abstract] [Full-text]
  48. Association study on the NAPG gene and bipolar disorder in the Chinese Han population.
    Neurosci Lett, 457(3): 159-62. [Abstract] [Full-text]
  49. Genetic association analysis of serotonin 2A receptor gene (HTR2A) with bipolar disorder and major depressive disorder in the Japanese population.
    Neurosci Res, 64(2): 231-4. [Abstract] [Full-text]
  50. Evidence-based guidelines for treating bipolar disorder: revised second edition--recommendations from the British Association for Psychopharmacology.
    J Psychopharmacol, 23(4): 346-88. [Abstract] [Full-text]
  51. Use of contraceptive methods among women treated for bipolar disorder.
    Arch Womens Ment Health, 12(3): 183-5. [Abstract] [Full-text]
  52. Parenting an adult child with bipolar disorder in later life.
    J Nerv Ment Dis, 197(5): 298-304. [Abstract] [Full-text]
  53. Chronic lithium treatment decreases NG2 cell proliferation in rat dentate hilus, amygdala and corpus callosum.
    Prog Neuropsychopharmacol Biol Psychiatry, 33(3): 503-10. [Abstract] [Full-text]
  54. Reliability of the Mood Disorder Questionnaire: comparison with the Structured Clinical Interview for the DSM-IV-TR in a population sample.
    Aust N Z J Psychiatry, 43(6): 526-30. [Abstract] [Full-text]
  55. Evaluation of treatment in 35 cases of bipolar suicide.
    Aust N Z J Psychiatry, 43(6): 503-8. [Abstract] [Full-text]
  56. A double-blind, placebo-controlled pilot study of galantamine to improve cognitive dysfunction in minimally symptomatic bipolar disorder.
    J Clin Psychopharmacol, 29(3): 291-5. [Abstract] [Full-text]
  57. Chronotype and body composition in bipolar disorder.
    Chronobiol Int, 26(4): 780-8. [Abstract] [Full-text]
  58. Peptic ulcer and mental disorders among adults in the community: the role of nicotine and alcohol use disorders.
    Psychosom Med, 71(4): 463-8. [Abstract] [Full-text]
  59. Neurocognitive Dysfunction in Bipolar and Schizophrenia Spectrum Disorders Depends on History of Psychosis Rather Than Diagnostic Group.
    Schizophr Bull. [Abstract] [Full-text]
  60. Schizophrenia genetics: new insights from new approaches.
    Br Med Bull. [Abstract] [Full-text]
  61. Pathways between nonmedical opioid use/dependence and psychiatric disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions.
    Drug Alcohol Depend, 103(1): 16-24. [Abstract] [Full-text]
  62. Gender differences in veterans health administration mental health service use.
    Womens Health Issues, 19(3): 176-84. [Abstract] [Full-text]
  63. Cognitive deficits in middle-aged and older adults with bipolar disorder and cognitive complaints: comparison with mild cognitive impairment.
    Int J Geriatr Psychiatry, 24(6): 624-31. [Abstract] [Full-text]
  64. Bipolar disorder and dopamine dysfunction: an indirect approach focusing on tardive movement syndromes in a naturalistic setting.
    BMC Psychiatry, 9: 16. [Abstract] [Full-text]
  65. Concept of Representation and Mental Symptoms. The Case of Theory of Mind.
    Psychopathology, 42(4): 219-228. [Abstract] [Full-text]
  66. The Road to DSM-V. Bipolar Disorder Episode and Course Specifiers.
    Psychopathology, 42(4): 209-218. [Abstract] [Full-text]
  67. Case-control studies show that a non-conservative amino-acid change from a glutamine to arginine in the P2RX7 purinergic receptor protein is associated with both bipolar- and unipolar-affective disorders.
    Mol Psychiatry, 14(6): 614-20. [Abstract] [Full-text]
  68. Proteomic analysis of membrane microdomain-associated proteins in the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder reveals alterations in LAMP, STXBP1 and BASP1 protein expression.
    Mol Psychiatry, 14(6): 601-13. [Abstract] [Full-text]
  69. Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: implications for schizophrenia, autism and cancer.
    Mol Psychiatry, 14(6): 563-89. [Abstract] [Full-text]
  70. Therapeutic Drug Monitoring of Lithium in Patients With Bipolar Affective Disorder: Experiences From a Tertiary Care Hospital in India.
    Am J Ther. [Abstract] [Full-text]
  71. Expressed emotion moderates the effects of family-focused treatment for bipolar adolescents.
    J Am Acad Child Adolesc Psychiatry, 48(6): 643-51. [Abstract] [Full-text]
  72. Relation between amygdala structure and function in adolescents with bipolar disorder.
    J Am Acad Child Adolesc Psychiatry, 48(6): 636-42. [Abstract] [Full-text]
  73. Increased intrasubject variability in response time in youths with bipolar disorder and at-risk family members.
    J Am Acad Child Adolesc Psychiatry, 48(6): 628-35. [Abstract] [Full-text]
  74. Neuropsychological impairment and psychosis in mania.
    J Clin Exp Neuropsychol, 31(5): 523-32. [Abstract] [Full-text]
  75. Sinus node dysfunction in association with chronic lithium therapy: a case report and review of literature.
    Am J Ther, 16(3): 274-8. [Abstract] [Full-text]
  76. Analysis of a t(18;21)(p11.1;p11.1) translocation in a family with schizophrenia.
    J Hum Genet. [Abstract] [Full-text]
  77. Use and safety of antipsychotic drugs during pregnancy.
    J Psychiatr Pract, 15(3): 183-92. [Abstract] [Full-text]
  78. Cognitive impairment in early and late bipolar disorder.
    Am J Geriatr Psychiatry, 17(6): 508-15. [Abstract] [Full-text]
  79. Candidate region linkage analysis in twins discordant or concordant for depression symptomatology.
    Am J Med Genet B Neuropsychiatr Genet, 150(4): 581-4. [Abstract] [Full-text]
  80. Detailed analysis of the serotonin transporter gene (SLC6A4) shows no association with bipolar disorder in the Northern Swedish population.
    Am J Med Genet B Neuropsychiatr Genet, 150(4): 585-92. [Abstract] [Full-text]
  81. Gene expression and association analyses of the phosphodiesterase 4B (PDE4B) gene in major depressive disorder in the Japanese population.
    Am J Med Genet B Neuropsychiatr Genet, 150(4): 527-34. [Abstract] [Full-text]
  82. "Mixed hypomania" in children and adolescents: is it a pediatric bipolar phenotype with extreme diurnal variation between depression and hypomania?
    J Affect Disord, 116(1): 12-7. [Abstract] [Full-text]
  83. Maintenance of response following stabilization of mixed index episodes with olanzapine monotherapy in a randomized, double-blind, placebo-controlled study of bipolar 1 disorder.
    J Affect Disord, 116(1): 43-50. [Abstract] [Full-text]
  84. Severity of bipolar disorder is associated with impairment of response inhibition.
    J Affect Disord, 116(1): 30-6. [Abstract] [Full-text]
  85. Neurocognitive and symptomatic predictors of functional outcome in bipolar disorders: a prospective 1 year follow-up study.
    J Affect Disord, 116(1): 37-42. [Abstract] [Full-text]
  86. Medical and substance use comorbidity in bipolar disorder.
    J Affect Disord, 116(1): 64-9. [Abstract] [Full-text]
  87. Relationship among latitude, climate, season and self-reported mood in bipolar disorder.
    J Affect Disord, 116(1): 152-7. [Abstract] [Full-text]
  88. Age-at-onset in bipolar-I disorder: mixture analysis of 1369 cases identifies three distinct clinical sub-groups.
    J Affect Disord, 116(1): 23-9. [Abstract] [Full-text]
  89. Reduced insight in bipolar I disorder: neurofunctional and neurostructural correlates: a preliminary study.
    J Affect Disord, 116(1): 56-63. [Abstract] [Full-text]
  90. Cognitive functioning of bipolar I patients and relatives from families with or without schizophrenia or schizoaffective disorder.
    J Affect Disord, 116(1): 70-9. [Abstract] [Full-text]
  91. Diagnostically irrelevant information can affect the likelihood of a diagnosis of bipolar disorder.
    J Affect Disord, 116(1): 148-51. [Abstract] [Full-text]
  92. Comparison of mapping quantitative theta encephalograms during directed and required visual-verbal activity and passive period in children with different disorders of speech-language functioning.
    Exp Brain Res, 195(4): 569-74. [Abstract] [Full-text]
  93. Age at onset of first episode and time to treatment in in-patients with bipolar disorder.
    Br J Psychiatry, 194(6): 559-60. [Abstract] [Full-text]
  94. White matter microstructural impairments and genetic liability to familial bipolar I disorder.
    Br J Psychiatry, 194(6): 527-34. [Abstract] [Full-text]
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Bipolar Research Today Archive:

Volume 1 (2004)
  Issue 1 (September)
  Issue 2 (October)
  Issue 3 (November)
  Issue 4 (December)

Volume 2 (2005)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
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  Issue 12 (December)

Volume 3 (2006)
  Issue 1 (January)
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  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 4 (2007)
  Issue 1 (January)
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  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
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  Issue 11 (November)
  Issue 12 (December)

Volume 5 (2008)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 6 (2009)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)
  Issue 4 (April)
  Issue 5 (May)
  Issue 6 (June)
  Issue 7 (July)
  Issue 8 (August)
  Issue 9 (September)
  Issue 10 (October)
  Issue 11 (November)
  Issue 12 (December)

Volume 7 (2010)
  Issue 1 (January)
  Issue 2 (February)
  Issue 3 (March)



Bipolar Books

Healing Depression & Bipolar Disorder Without Drugs: Inspiring Stories of Restoring Mental Health Through Natural Therapies

Healing Depression & Bipolar Disorder Without Drugs: Inspiring Stories of Restoring Mental Health Through Natural Therapies